Āé¶¹“«Ć½

The history of humanity in our genes

From double-jointedness to the transmission of leukaemia in the womb, Sam Kean explores humanity's history through genetics in The Violinist's Thumb

See more: An illustrated version of this article will be published within the next two weeks on our CultureLab books and arts blog

THE waitress stopped as she passed my table. ā€œIs that a mystery you’re reading? Cover looks like it.ā€ ā€œNo,ā€ I answered. ā€œIt’s a fast-paced, breezy romp through history using DNA as a unifying theme – it’s nerd-vana.ā€

In truth, it’s a wonder that I broke away for long enough to converse at all, given the wealth of engaging information contained in every paragraph of this book.

In it, science writer Sam Kean sets out to explain many human phenomena in the light of DNA, speeding from personality quirks of early geneticists to evidence for interbreeding between Neanderthals and humans.

The book’s title refers to Kean’s retrospective diagnoses of medical conditions in historical figures, in this case attributing Ehlers-Danlos syndrome to Niccolò Paganini, the violinist. One symptom is double-jointedness, which would help explain his virtuosic abilities.

There are a few problems. When explaining the transmission of leukaemia between a woman and her fetus, Kean asserts that maternal-fetal microchimerism does not happen. In fact, have some of our mother’s – and, if you are a mother, your child’s – cells within us. Kean’s example is just a tragic demonstration of the phenomenon, as cancer cells are among those that cross the placental barrier.

Despite some slips like this, Kean’s book is engaging. I couldn’t help scribbling on pages, with comments equally split between ā€œooh, interesting!ā€ and ā€œdouble check thisā€. Either way, The Violinist’s Thumb kept me hooked.

The Violinist’s Thumb

Sam Kean

Doubleday/Little, Brown

Topics: Books and art

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