DAMAGE to a gene called Bcl10 may trigger many common cancers, say
researchers in Britain.
Martin Dyer and his colleagues at the Institute of Cancer Research in Sutton,
Surrey, found the faulty gene in tissue from lung, colon and testicular tumours
(Cell, vol 96, p 35). The normal Bcl10gene serves as a
“sentinel”, liquidating damaged cells. “But when it’s damaged, Bcl10
actively turns cells malignant,” says Dyer.
