THE next generation of AIDS drugs may be free of two dreaded side effects.
Today’s drugs can cause disfiguring fat redistribution in the body and diabetes.
But researchers in Missouri have pinned down the reason for these problems, and
say that tinkering with the chemical make-up of the drugs could banish the side
effects for good.
People with HIV are given drugs called protease inhibitors which are designed
to gum up HIV protease, an enzyme that the virus needs to replicate. But they
can also cause metabolic disorders, including a redistribution of fat from the
face and limbs to the…
