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Health

Once a day keeps HIV at bay

By Claire Ainsworth

30 September 2000

THE discovery that one anti-HIV drug remains active much longer in cells than
anyone had thought could transform the lives of people with HIV. Researchers say
that patients could take their pills just once a day, at bedtime, instead of
having to keep to a complicated daily schedule.

Researchers from three hospitals in northern Italy designed the new regime.
They based it on findings by other scientists that the anti-HIV drug lamiduvine
lasts between 13 and 15 hours inside cells, compared with just an hour or two in
the bloodstream. The behaviour of the drug inside cells is critical, as…

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