Âé¶¹´«Ã½

Slimming jab

13 September 2003

FAT people lose weight after injections of a naturally occurring gut hormone called PYY3-36.

In research published last week, 24 volunteers given a 90-minute infusion of PYY3-36 ate one-third fewer calories than people given a placebo irrespective of whether they were obese or not (The New England Journal of Medicine, vol 349, p 941).

PYY3-36 is produced after eating, and acts on a part of the brain called the hypothalamus to reduce appetite. It has already been shown to help obese rats slim (Âé¶¹´«Ã½, 9 August, p 38).

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