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Technology

Oil and water mix for better drugs

By Rachel Nowak

22 March 2005

MEDICINES that could be very useful, but which have toxic side effects, could become safer and more widely available thanks to some unexplained chemistry.

Many potential drugs are fat-soluble chemicals that do not dissolve or mix well with water, blood and other body fluids. To turn them into medicines, they are usually dissolved in a “carrier” oil, and then an additive such as a detergent is used to disperse the oily solution in water. A more sophisticated approach is to encase the drugs in microscopic water-soluble particles. But the carrier oils and additives can have unpleasant side effects, trigger allergic…

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