THE sins of the fathers are, indeed, visited on subsequent generations. Nutrition and smoking in early life may influence the health of men’s sons and grandsons, a new study has revealed.
These striking inherited effects are thought to be due to subtle chemical changes to DNA known as “epigenetic” modifications (see “Mapping the epigenome”). And they could have big implications for public health: the behaviour of today’s children, for example, may be stacking up problems for future generations.
Marcus Pembrey, a clinical geneticist at University College London, and colleagues at UmeÃ¥ University in Sweden, have two lines of evidence…
