Âé¶¹´«Ã½

Health

One drug trial, six men, disasterÂ…

By Shaoni Bhattacharya and Andy Coghlan

22 March 2006

Âé¶¹´«Ã½. Science news and long reads from expert journalists, covering developments in science, technology, health and the environment on the website and the magazine.

What went wrong?

(Image: Getty)

AT 8 o’clock on the chilly morning of Monday 13 March, eight healthy young men were injected as part of a drug safety trial. The volunteers were all paid for their participation, but no one suspected what lay in store. Within minutes six of them were reportedly writhing in pain, tearing at their clothes, screaming and retching. The two others waited in terror for their turn, but they were in luck: they had been given placebos and escaped.

It is unprecedented for such serious and rapid symptoms to appear in all volunteers given a drug…

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