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Life

Three-pronged plot to keep HIV at bay

By Andy Coghlan

5 April 2006

ATTACKING HIV using a combination of anti-retroviral drugs has proved resoundingly successful at keeping the virus at bay. Now an experimental therapy is being proposed that will apply the same concept from within the cells HIV attacks and destroys, by arming the cells to fight the virus on three fronts.

“We don’t want to rely on a single mechanism,” says John Rossi, head of the team developing the therapy at the Beckman Research Institute of the City of Hope in Duarte, California. “So we’ve developed what we call a triple vector against HIV.” If one strategy fails, another will kick in and thwart the virus.…

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