Âé¶¹´«Ã½

Technology

Delivering drugs at the flick of a switch

13 February 2008

COATINGS that dissolve when exposed to a voltage could be used to release drugs implanted in the body at specific times.

Researchers at the Massachusetts Institute of Technology alternately dipped a glass substrate in a positively charged anticoagulant drug and a solution of negatively charged nanoparticles to build up a series of alternating layers. Applying a voltage caused the exposed nanoparticle layer to dissolve, releasing the drug. When the voltage was switched off, the layers stopped dissolving (Proceedings of the National Academy of Sciences, ).

Such a device could be implanted in a patient’s body along with a…

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