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Health

How biological 'alchemy' can change a cell's destiny

By Peter Aldhous

18 June 2008

Âé¶¹´«Ã½. Science news and long reads from expert journalists, covering developments in science, technology, health and the environment on the website and the magazine.

CALL it biological alchemy: specialist pancreatic cells that secrete digestive enzymes have been converted directly into insulin-producing beta cells. Meanwhile, epithelial cells from the back of the eye have been coaxed into becoming a versatile, new type of stem cell.

Both advances, reported last week in Philadelphia, Pennsylvania, at the , may take us closer to a “regenerative” approach to repairing damaged tissue. And both are products of a wave of enthusiasm that has built since Shinya Yamanaka of Kyoto University in Japan showed that it is possible to “reprogram” adult cells…

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