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From Simon Goodman, Darmstadt, Germany

Celebrating your 60th anniversary, you nominate the most influential innovations of the past 60 years. I will not be alone in reminding your readers that two of the most significant inventions of the last 60 years are DNA cloning and sequencing ( and ), and the monoclonal antibody ().

Both these technologies opened previously inaccessible windows into living things.

The editor writes:

• The inventions were chosen by our panel of science historians.