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Letter: Semaglutide side effect: The hangry man theory

Published 7 May 2025

From Paul Davis, Maidencombe, Devon, UK

I read with interest about the “middle-class microdoser” of the weight-loss drug Wegovy, who lost 20 kilograms of body weight over nine months. That is a long time to be eating less than his body needed each day. He reflected on becoming grumpy over that time and wondered if it was a side effect of the drug. Could the reason be simpler? As the father of an always-hungry teen, I know that when my son is low on nutrition, he gets grumpy. I see the same reaction in myself too(Letters, 19 April).

Issue no. 3542 published 10 May 2025

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